Antiangiogenic Therapy Improved Cancer Survival

Again this is from Dr. William Li’s presentation at TED 2010, see here.  These charts show the improvements of cancer survival rate since 2004.  Very impressive.

cancer survival rate before anti angiogenic therapy 300x229 Antiangiogenic Therapy Improved Cancer Survival

Cancer survival rate with chemo and surgical therapy

after antiangiogenic therapy 300x231 Antiangiogenic Therapy Improved Cancer Survival

Cancer survival rate since antiagniogenic therapy in 2004

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What can anti-angiogenesis therapy do?

Lately, I’ve been reading a lot about angiogenesis.  Here’s my notes on how this process works.  The most authority information’s are National Cancer Institute and the Angiogenesis Foundation.

Angiogenesis is the formation of new blood vessels and is controlled by chemicals in the body. New blood vessels “feed” cells in our body with oxygen and nutrients, allowing these cells to grow.  Those cells include good ones, e.g. healing a cut on the skin, and bad ones, e.g. cancer/tumor cells and fat tissues.

The most exciting thing is that angiogenesis can be controlled by certain chemicals produced in the body. Some of these chemicals stimulate angiogenesis, and other chemicals, called angiogenesis inhibitors, signal the process to stop.  Angiogenesis inhibitors may not necessarily kill tumors, but instead may keep tumors stable.

When cancer cells have started growing and spreading, angiogenesis inhibitor therapy will only be most effective when combined with other therapies.

Cancer/tumor cells are common in us.  When they don’t grow excessively, they coexist well with other cells in our body. When the angiogenesis process is out of balance, or the angiogenesis stimulating and inhibiting chemicals are out of balance, cancer cells go crazy.

As the old saying goes: An ounce of prevention is worth a pound cure.

Keeping the angiogenesis stimulating and inhibiting chemicals in balance is the key in the prevention.  I guess this is the basis of  Dr. William Li’s thesis on “Eat to starve cancer”.

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A List of Anti-angiogenic Foods

After much requests, Dr. William Li showed the slide with a list of Anti-angiogenic foods.

Antiangiogenic food A List of Anti angiogenic Foods

Some are a bit exotic such as ginseng and sea cucumber and could be expensive to acquire. Most of them are inexpensive and common food that we consume daily.

I’m trying to make sense of the list by grouping them.  Some of them can be taken in volume, e.g. fruits, drink and vegetables. Others cannot have a significant amount in your daily dietary, e.g. spices, ginseng, olive oil and grape seed oil.

Dietary sources of naturally-occurring anti-angiogenic substances
Fruits Spices Drink Vegetable Others
Strawberries Lavender Red wine Pumpkin Dark chocolate
Blackberries Parsley Green tea Bok choy Sea cucumber
Raspberries Garlic Kale Tuna
Blueberries Nutmeg Soy beans Ginseng
Oranges Licorice Artichoke Olive oil
Grapefruit Turmeric Maitake mushroom Grape seed oil
Lemons Tomato
Apples
Pineapple
Cherries
Red grapes

I’m not sure whether Dr. William Li had tested all common food exhaustively. But there are things conspicuously missing, such as coffee, white grapes.  For me, I’d swap those unlisted for the listed here.  It’s better to err on the side of caution.

Now it’s also known that some food if taken in large quantity contain bad or toxic substance, e.g. Tuna has high concentration of  mercury; grape seed oil is ~70% linoleic acid (omega-6), which is believed to be a significant contributor to oxidization of LDL and Heart Disease.

There must be a fine balance.

I guess the old adage: an apple a day, keep doctor away, should mean that it’s safe to consume large quantity of apples.

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Eat to Starve Cancer

This is a most intriguing thinking on curing cancer with food. It’s based on solid modern medical theory and practice. The idea is to control the AngioGenesis process.

As summarized by another doctor:

The more vegetable real food one eats, the closer one comes to the conditions under which our bodies developed. The more processed food we eat, the more we remove ourselves from our birthright to good health.

You can draw you own conclusion after watching this video, presented by the founding doctor of Anti-AngioGenic therapy Dr. William Li.

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